During the past half decade there has been a paradigm shift in the view of acute kidney disease that has resulted in a change in nomenclature from the older term, “acute renal failure,” to “acute kidney injury” (AKI). This article reviews the new criteria for diagnosis and staging of AKI and summarizes the current understanding of the many causes of AKI and the approach to diagnosis and management.
aRenal-Electrolyte Division, University of Pittsburgh School of Medicine, A-919 Sciafe Hall, 3550 Terrace Street, Pittsburgh, PA 15213, USA
bRenal Section, VA Pittsburgh Healthcare System, Room 7E123 (111F-U), University Drive Division, Pittsburgh, PA 15240, USA
Corresponding author. Renal Section, VA Pittsburgh Healthcare System, Room 7E123 (111F-U), University Drive Division, Pittsburgh, PA 15240.